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7-pyridin-2-yl-N-(3,4,5-trimethoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule belonging to the pyrrolopyrimidine class. It is an experimental compound known as a potent and selective inhibitor of focal adhesion kinase (FAK), also called protein tyrosine kinase 2 (PTK2). FAK is a non-receptor tyrosine kinase involved in cellular adhesion and signal transduction pathways that regulate cell migration and survival. Inhibition of FAK has been investigated for potential anti-cancer effects due to its role in tumor progression and metastasis. This compound has not been approved for clinical use but is used in research settings as a chemical probe or tool compound to study FAK biology.[1][3][6][7]
- Other names
- 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE7-(pyridin-2-yl)-N-(3,4,5-trimethoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine7-(pyridin-2-yl)-N-(3,4,5-trimethoxyphenyl)pyrrolo[2,3-d]pyrimidin-2-aminoCAS No. 863599–15–9
02
Targets
FAK (Focal adhesion kinase)
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